Genetic Engineering & Biotechnology News

JUL 2016

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.

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34 | JULY 2016 | GENengnews.com | Genetic Engineering & Biotechnology News For more information, visit our website (GENengnews.com), click on New Products, and search through our comprehensive new products database. NEW PRODUCTS qPCR Set-Up and Miniaturization The D300e provides picoliter to microliter noncontact dispensing of liquids directly into assay plates, and the software now features a PCR Wizard that guides the user through qPCR set- up. An updated software package ofers new functionality and device's fexibility for genomics workfows. Accurate and reproducible plate generation and low volume dispensing capability of the D300e provides a convenient solution for the miniaturization of qPCR assays, allowing up to a fve-fold reduction in assay vol- umes without any loss of data quality. The instrument has the ability to use high capacity D4+ cassette for reagent dispensing—increasing the capacity from 10 μL to 200 μL for small molecule and biomolecule dispensing. Tecan www.tecan.com Motorized Z-Axis Microscope Focus Blocks The FB series of Z-axis motor- ized focus blocks ofers precise and repeatable positioning of loads with a weight of up to 14 kg. These Z-axis motorized focus blocks deliver repeat- ability (± 0.7 µm) and precision (± 20 nm) required for almost any imaging application. Even with a full load, focus blocks may be driven between 1 and 14 mm/sec over a travel range of 38 mm. The FB series motorized focus blocks can be controlled via Prior's ProScan III control system. This control system integrates into a wide variety of imaging ap- plications, potentially allowing every component of the imaging system to be controlled from a central point. Prior Scientifc www.prior-scientifc.co.uk Instrument Control Software LabX® instrument control software can help you close gaps in traceability, total cost-of-ownership, and time savings. Instruments outftted with LabX can connect roughly one-third of available laboratory instrument types to one management system. This ability to con- nect and archive data helps to eliminate administrative bottlenecks and the risk of transcription and recalculation error inherent in manual processing. It can also help ensure that all data produced by lab equipment meets fundamental quality elements and criteria for scien- tifc soundness to meet Good Manu- facturing Practices. This saves a signifcant amount of time, allows automatic results evaluation, and stores complete datasets—including meta data—for later reference and use, which can be particularly important for a quality or regulatory audit. Additionally, data transfer occurs through one point, which can further minimize efort expended on IT infrastructure. Mettler Toledo www.mt.com Maternal Serum II Control Liquichek Maternal Serum II Control is a frozen liquid human serum- based material designed to moni- tor the precision of laboratory test procedures used during maternal serum second trimester screening. Liquichek Maternal Serum II Control includes AFP, Free Estriol, hCG, and Inhibin A, making it ideal for labora- tories performing triple or quadruple marker screening. The liquid form eliminates the need for reconstitu- tion, increasing efciency and allowing samples to be treated the same way as patient specimens. The serum control is designed for use on various instruments and reagent systems and has a three-year shelf life when stored at -20 to -70°C, in addition to an open-vial stability of 30 days when stored between 2°C to 8°C. BioRad www.bio-rad.com Workfow Solution for Predicting Human Pharmacokinetics Version 2 of the in silico modelling solution, chemPK™, which predicts human pharmacokinetics directly from chemical structure, is now available. The original version of chemPK was able to predict hu- man pharmacokinetics following administration of a single oral dose. Version 2 now has the ability to predict human pharmacokinetics following administration of both oral and intravenous dose. It is also able to simulate repeat-dose administration and so is more relevant to the typical dosing regi- men within the clinic. chemPK uses a PBPK (physiologically based pharmacokinetic) modelling approach, which is an extremely robust technique. The software is easy to implement and use. It operates on the freely available KNIME Analytics Platform for workfow management, which facilitates integration with a wide range of other cheminformatics, analytics, and modelling tools. Cyprotex www.cyprotex.com 3D Cell Culture Vessels The CELLSTAR cell culture vessels with cell-repellent surface are for cultivat- ing cells to form three-dimensional structures. Good results can be achieved, particularly when they are used with technology from cooperation partner Nano3D Biosciences. This technology is based on the magnetization of cells us- ing nanoparticles that attach themselves to the cell membrane. The development of three-dimensional spheroids or ring structures is initiated by briefy applying magnets. The cell culture vessels with cell-repel- lent surface efectively prevent the adhesion of semi-adherent and adherent cell lines, they are ideal for suspension cultures and for cultivating spheroids, stem cell aggregates, and gel-based 3D cultures. The cell culture fasks come in three diferent formats: 25 cm², 75 cm², and 175 cm² growth area—as both standard and flter-top cell culture fasks. Greiner Bio-One www.gbo.com

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