Genetic Engineering & Biotechnology News

AUG 2017

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D community with critical information on the tools, technologies, and trends that drive the biotech industry.

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30 | AUGUST 2017 | GENengnews.com | Genetic Engineering & Biotechnology News For more information, visit our website (GENengnews.com), click on New Products, and search through our comprehensive new products database. New Products Microencapsulation Droplet System The Telos® droplet system, designed for high throughput and easy scale up, provides scientists with excellent modular component process control system, and the ability to choose from a range of particle diameters between 10–50 µm on a single piece of hardware. PLGA, or poly(lactic-co-glycolic acid), is a copolymer commonly used for drug microencapsu- lation. Precise manipulation of particle size, shape, and architecture is extremely important to the efficacy of the candidate drug. However, conventional emulsion-based batch methods result in uneven API distribution and particle polydispersity, requiring additional size-selection and leading to low particle yields and significant loss of API. Dolomite's continuous flow microfluidic method overcomes these obstacles, providing almost 100% encapsulation within precisely controlled, monodisperse PLGA particles, in a single repro- ducible step. Dolomite www.dolomite-microfluidics.com Flow-Cytometry Pump Hydrodynamic focusing of individual cells is achieved only with the aid of a con- tinuous and precise sheath flow. The speed of the sheath flow determines the speed of the cells and must be constant. Even small deviations lead to measure- ment errors. Micro-annular gear pumps are character- ized by low pulse and low shear delivery, minimal dead volume, and a long service life. Because of their low weight and compact design, they are ideally suited for integration in analytical instruments. Due to chemical-resistant materials used for mzr pumps, a chemical sterilization is possible. Besides the delivery of the sheath flow, these pumps can be used for cell and particle suspensions. HNP Mikrosysteme www.hnp-mikrosysteme.de Flow-Cytometry System The new Aurora advanced flow-cytometry system enables a 20+ color capability, using three excitation lasers and 50 chan- nels. An innovative system design, which includes excitation optics and compact semiconductor detector modules with high quantum efficiency, allows for the implementation of more detection chan- nels per laser than conventional flow-cy- tometry systems. Depending on the laser excitation wavelength, this permits detection of any fluorescence emission in the 400–900nm range without having to change optical filters. Aurora's optical design and unmixing algorithm combine to enable the use of a wide array of dyes, including those with highly overlapping spectra. Cytek Biosciences www.cytekbio.com Monoclonal Antibodies The Binding Site has recently introduced new mAbs fo- cused on infectious diseases, including CMV, hepatitis (A, B, C, and D), herpes, HIV, rubella, and toxoplasmosis. Availability of these products will enhance the needs of biopharmaceutical, clinical, and life-science researchers, along with in vitro diagnostic manufacturers. All of these antibodies exhibit outstanding degrees of specificity, while demonstrating high levels of purity, extended shelf-life stability, and lot-to-lot consistencies. The infectious disease mAbs are all available in a standard-sized 1.0-mg fill format, while the rest come in a 0.2-mg fill format. Bulk packaging and customer-specific packaging options are available as well. The Binding Site www.immunologicals.com High-Performance Fume Hoods UniFlow AireStream low-flow high-performance fume hoods feature an exclusive all- composite resin construction that is chemical-resistant, flame-retardant, lightweight, and meets UL 1805, SEFA 1, Ashrae 110, and ANSI Z9.5 standards. These hoods have a molded one-piece, seamless, composite resin interior fume chamber that has all coved corners and is white for superior light reflectivity. Available in sizes from 30" to 96" wide and in depths of 24" to 48", and in CAV (air bypass) or VAV (restricted bypass) models. A wide selection of accesso- ries and services are optional to meet exact user requirements. HEMCO www.hemcocorp.com Mass Spec Enzyme MilliporeSigma's ad- vanced proteomics-grade SOLu-Trypsin is a solution- stable enzyme for mass spectrometry. Designed to be stable in solution when refrigerated, SOLu-Trypsin can be used immedi- ately without preparation. Other forms of trypsin require thawing or reconstitution and must be discarded if not used immediately. SOLu-Trypsin allows excess prod- uct to be saved for future use, thus eliminating unnecessary waste and cost. SOLu-Trypsin is formulated with a high-purity recombinant trypsin, free of chymotryptic activity, to ensure high fidelity digestion. MilliporeSigma www.emdmillipore.com

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