Genetic Engineering & Biotechnology News

JAN15 2018

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D community with critical information on the tools, technologies, and trends that drive the biotech industry.

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For more information, visit our website (GENengnews.com), click on New Products, and search through our comprehensive new products database. New Products 26 | JANUARY 15, 2018 | GENengnews.com | Genetic Engineering & Biotechnology News Best of the Web All of the links to the URLs described above are posted on GEN's website, www.GENengnews.com. To suggest a website for Best of the Web, please send the URL to Taralyn Tan (ttan@GENengnews.com). Key Strong Points Weak Points Excellent Ratings Very Good Good 9 – HHHH HHH HH GPCRdb HHHH gpcrdb.org 9 Easy browsing through receptors, interactive features – Nothing major GPCRdb is a vast catalog of G-protein–coupled receptors and includes information about the receptors themselves, their signaling proteins, ligands, crystal constructs, and their po- tential drug targets and therapeutic uses. The website is easy to navigate and has extensive documentation and tutorials that make it even more intuitive to use. The website contains a wide range of tools, allowing the user to explore topics such as GPCR structures, interactions with their ligands, and mutations that can potentially affect signaling. A particularly interesting feature allows the user to select individual GPCRs or entire families and construct phylogenetic trees in order to visualize the evolution of these receptors better. GPCRdb is beautifully constructed, easy to use, and provides an enormous amount of informa- tion useful for any biologist studying this large class of receptors. Cancer Prevention and Control Research Network HHHH cpcrn.org 9 Easy to navigate, accessible training modules The Cancer Prevention and Control Research Network (CP- CRN), part of the Prevention Research Centers from the Center for Disease Control, aims to bring cancer prevention strategies out of the lab and into the community, particularly to under- represented groups. The website details several projects that the CPCRN is currently working on, which include programs such as smoking cessation assistance, wider implementation of HPV vaccines, and enhanced cancer screening. The website also provides resources such as an interactive training curriculum, which describes methods of imple- menting evidence-based cancer prevention methods into a wider community setting. Cancer research is expansive, with countless scientists trying to determine how to eradicate it biologically. However, there are at least a few things we can do to help counteract this disease, such as requiring routine screenings and avoiding common carcinogens like cigarettes. The CPCRN is dedicated to better serving communities through this public health approach, and providing invaluable resources to others who hope to do the same. Hippocampome HHHH hippocampome.org/php/morphology.php 9 Very organized, updated frequently – Content should expand to include other brain regions Neurons are often depicted in the same way—a prominent cell body, with dendrites protruding from one end and a single long axon winding from the other end. However, in reality, neurons are incredibly diverse, even within a single brain area. Hippo- campome consolidates information about neurons specifically found in the hippocampus, and catalogs the diverse morphol- ogy, electrophysiology, connectivity, and molecular markers of these neurons. The website nicely displays a large amount of information about the variety of neurons found in this brain region by consolidating it into tables that are clearly marked and easy to follow. The tables are heavily referenced, which allows users to delve more deeply into specific cell types based on any of the characterizing features that are described. Hippocampome is an excellent website that is thoughtfully organized and very informative about the diverse types of neurons that can be found in this memory center of the brain. Instant Anatomy HH www.instantanatomy.net 9 Very well organized – Limited accessibility without paid subscription Instant Anatomy is a well organized and easy-to-navigate resource for learning about human anatomy. The website divides the body into five broad categories: head and neck, thorax, abdomen, upper limb, and lower limb. Within each of these broad categories are fur- ther subdivisions, allowing the user to explore more specific features such as organs, nerves, and vasculature residing within that system. The website has a quiz feature that allows users to test their knowl- edge and additional information in the form of lectures and both audio and video podcasts. There are also accompanying Apple and Android apps for users on the go. Unfortunately, there are limited ques- tions and podcasts available for users who are not subscribers. But for a monthly fee, subscribers obtain access to the full materials provided on the site. Even with the limited free resources, Instant Anatomy is a great resource for refreshing your knowledge of human anatomy. The Biology Project HHH www.biology.arizona.edu 9 Tutorials are helpful and informative – Site design is a little outdated The Biology Project, from the University of Arizona, is a collection of problem sets and tutorials for biology students. The problem sets cover a wide range of topics, from basic biochemistry and cell biology to develop- mental biology and immunology. If the user selects an incorrect answer, the website provides a refresher on the material covered in the question—allowing the user to dis- cern why they were incorrect before being able to try the question again. In addition to the problem sets, the website also provides detailed tutorials on the topics that are covered and activities that teachers can do with their students in class. Although the website itself isn't flashy, the problem sets are an excellent tool for students or for anyone wanting a quick way to refresh their knowledge in broad biological topics. Zebrafish International Resource Center HHH zebrafish.org 9 Variety of lines, links to additional resources – Nothing major If you've been searching for that perfect zebrafish, or wondering why your zebrafish are looking green around the gills, look no further than the Zebrafish International Resource Center, from the University of Oregon. The website contains extensive catalogs of ge- netically manipulated zebrafish lines that are available for purchase, and also allows users to order cDNA and antibodies. In addition to providing zebrafish, the web- site also contains a Health Services section where you can request diagnostic tests ranging from histopathology and bacteriology to necropsy and molecular assays. The zebrafish is a fascinating creature and an excellent model organism whose use in laborato- ries will only continue to expand. The Zebrafish International Resource Center is a great website to have handy for any scientists who are currently using or plan on using this model organism in their research.

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