Genetic Engineering & Biotechnology News

AUG 2013

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.

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Contents AUGUST 2013 • Biobusiness DrugDiscovery CorporateProfle 16 Hematologic Diagnostics GowiththeFlow Cover StillaPlace MakingSenseof SmallMolecules www.GENengnews.com 12 Metabolon has made a name for itself as a pioneer in metabolomics and is now moving forward with diagnostics. Bioprocessing forSteel andGlass NEWSInsideIndustry Scientists are using fow cytometry and related techniques to better diagnose hematopathological disorders. WallStreetBiobeat NEWSDiscovery&Development; BigNeedinIBD:Drugs toSlowProgression 30 NEWSBioprocessing 14 Tutorial Tutorial The infammatory bowel disease market is set for a shakeup. 20 RemovingtheReceptor DeconvolutionBottleneck 32 BiomarketTrends 15 Single-CellGenomics PoisedforGrowth Certain segments of the single-cell genomics market are set to grow more than 40% annually, according to DeciBio. NEWSProducts&Services; DEPARTMENTS CreativeAcquisitionin Biotech,TakeTwo Big pharma is not alone in its M&A; quests—smaller frms are also pursuing large biotech deals. withArrayCGH LegalAffairs 10 Researchers are looking beyond SNPs, assessing copy-number variation as a key contributor to genomic diversity. 24 RethinkingTrade SecretProtection 38 40 40 41 41 42 16 Now more than ever, biotech frms ought to evaluate how well they are protecting proprietary information. New Products Calendar of Events Company Index People in the News Classifed Best of the Web NovelCHO Suspension CellCultivation According to Finesse Solutions, its stirred-glass biorector is suitable for cell culture applications at the benchtop scale. OMICS Cover DivingDeep PointofView 6 Retrogenix says its microarray system helps users identify the receptors for many antibody ligands. Researchers increasingly look to standby glass and stainless steel bioreactors over single-use systems for certain projects. RT-PCR: Readyfor PrimeTime? Though it is a choice tool for many scientists, a relative consensus on how best to perform RT-PCR is still lacking. NEWSGenomics&Proteomics; 28 Translational Medicine 34 Molecular ImagingDriving Development Using pharmacoimaging and other approaches, scientists are better selecting lead candidates and improving clinical trial designs. NEWSMolecularDiagnostics 37 NEWSClinicalTrials Tutorial MembraneProtein MonoclonalAntibodies SDIX outlines an approach for the development of highperformance multipass membrane protein antibodies. 30 34

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