Genetic Engineering & Biotechnology News

OCT1 2012

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.

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Point of View ic food and antibiotechnology organizations. There are even more compelling reasons than pleasing their customers for apple growers and their trade groups to embrace the new technology: the experiences, both positive and negative, of other farming sec- tors in the recent past. Recombinant DNA Technology Consider, for example, the cautionary tale of the Kona coffee industry in Hawaii, which in 2008 pushed the Hawaii County Council to ban the growing of recombinant DNA-modi- fied beans on the Big Island. The growers felt that the use of the new technology would risk decades of building the reputation of Kona cof- fee as a brand. Beans developed using recombi- nant DNA technology may not qualify as "spe- cialty coffee," and therefore, it was feared that they would command a lower market price. The industry may now be singing a differ- ent tune. Big Island coffee growers are facing a dire threat to their crops that didn't exist four years ago: Infestations of the Coffee Berry Bor- er beetle, which evolves resistance to pesticidal sprays, were first discovered in Kona in 2010 and have now been confirmed in all parts of west Hawaii and in some other areas as well. Faced with the threat of devastation of their crops, the industry is now desperate for any measures to combat the beetle. Recombinant DNA technology has been widely and success- fully used in corn, cotton, papaya, and other crops to introduce resistance to pests. Hawaiian coffee farmers and their orga- nizations should have heeded the positive example of the Rainbow variety of papaya, Hawaii's fifth largest crop. By inserting a sin- gle gene from a virus into papayas, scientists have made them virus-resistant. Although the biological mechanism is different, the effect is similar to vaccination of people and animals using weakened or killed viruses. The recom- binant DNA-modified Rainbow papaya has resurrected Hawaii's $64 million-a-year indus- try, which was moribund 15 years ago because of the predations of papaya ringspot virus. Wheat farming offers yet another exam- ple. By 2004, Monsanto, the world's leader in the production of seeds for genetically engi- neered crops, had made substantial progress in the development of genetically engineered wheat varieties for North America. But sud- denly in that year, the company scrapped its wheat program in large part because of op- position from North American grain mer- chants and growers. European countries and Japan, which have traditionally imported about 45% of U.S. wheat exports, have been resistant to recombinant DNA-modified crops and food derived from them. However, American growers and millers have had a change of heart. Wheat farming is a struggling industry in the United States, in large part because it has not received the technological boost from recombinant DNA technology that has hugely benefited the corn and soybean sectors. U.S. wheat acre- age is down about one-third from its peak in the early 1980s, due to reduced profitability compared with alternative crops. Therefore, in 2006, a coalition of U.S. wheat industry organizations called for access to recombi- nant DNA-modified wheat varieties with en- hanced traits, and a survey released in 2009 by the U.S. national association of wheat growers found that more than three-quarters of U.S. farmers wanted access to genetically improved varieties with resistance to pests, disease, drought, and frost. Such varieties are important as plant sci- entists and farmers continue to battle diseases such as leaf rust, the world's most common wheat disease, which can lead to yield loss of up to 20%. In Kansas, the heart of the U.S. wheat belt, for example, leaf rust destroyed a shocking 14% of the wheat crop in 2007. Apple growers should take note of the les- sons learned by others the hard way. There is little doubt consumers will like and even pay a premium for the nonbrowning trait in apples. Instead of fighting the introduction of this improved, consumer-friendly prod- uct (as well as others that could follow), the apple growers' associations should sow the seeds of greater sales and security of their harvest by mounting a truthful, positive ad campaign to trumpet the new advances in molecular biology applied to their products. They should bear in mind that technophobia often breeds poisoned fruit. " Don't be trapped by dogma." – Steve Jobs T300 Open your mind… and your lab, to the next generation T300 universal controller. And most important, have the courage to follow your heart and intuition. They somehow already know what you truly want to become. Everything else is secondary. – Jobs, 2005 ([ -PULZZL ^L ILSPL]L [OH[ UV[OPUN PZ PTWVZZPISL 6\Y ÄYZ[ NLULYH[PVU ; WSH[MVYT JV\SK LHZPS` PU[LYJOHUNL NSHZZ ]LZZLSZ MYVT (WWSPRVU :HY[VYP\Z HUK 5): VY ZPUNSL \ZL 4PSSPWVYL 4VIP\Z ]LZZLSZ 5V^ PTHNPUL WS\NNPUN `V\Y ZLJVUK NLULYH[PVU ; PU[V H :THY[IHN VU H ., >H]L VY -PULZZL YVJRLY +YLHT H SP[[SL HUK SPZ[LU [V `V\Y PUULY IPVWYVJLZZPUN ]VPJL >OH[ KV `V\ want your lab to become? Freedom to do anything. ;VKH` `V\ KVU»[ ULLK [V IL[ `V\Y SHI VU VUL IPVYLHJ[VY WSH[MVYT *VU[HJ[ -PULZZL HUK ÄUK V\[ OV^ V\Y ; Z`Z[LTZ JHU IYPUN `V\ IPVWYVJLZZPUN ÅL_PIPSP[` 800-598-9515 finesse.com © Finesse Solutions, Inc., 2012. In Europe, call: +41 81 641 20 00. In Asia, call: +65 8322-8128. Genetic Engineering & Biotechnology News | genengnews.com | October 1, 2012 | 9

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