Genetic Engineering & Biotechnology News

OCT1 2012

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.

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VOLUME 32, NUMBER 17 Tools | Technologies | Trends CONTENTS Biobusiness Corporate Profile 14 SciLog Sees Big Promise in Acquisition Now, as the life sciences unit of Parker Hannifin, firm says it has easier access to global markets, distribution channels, and additional resources. NEWS Inside Industry Biomarket Trends 16 NGS On Way to Becoming 46 Critical Dx Platform Molecular pathologists are among the clinicians expected to embrace next-gen sequencing in the coming years. Wall Street Biobeat 18 Advice to Biofirms: Be Prepared, Plan Ahead As any good scout knows, advanced planning is essential to survival. NEWS Products & Services Drug Discovery 20 Automation Redefines Compound Management 52 Departments Point of View 6 Technophobia = Poisoned Fruit New variety of apple is highly resistant to enzymatic browning but not immune to concerns about consumer reaction to recombinant DNA technology. Legal Affairs 11 Safe Harbor Protects Post-Approval Activities Patented methods for determining the composition of drugs are dealt significant blow in recent decision. 64 84 85 85 86 Corporate Capabilities 81 New Products 84 Calendar of Events Company Index People in the News Classified Best Science Apps While automation has labs running more smoothly than ever, researchers need to remain on alert for the potential errors that lurk behind new technology. NEWS Discovery & Development Tutorial 23 Capturing the Clone Rockland developed antigamma globulin antibodies against mouse and rat heavy and light chain isotopes to ensure hybridomas are captured early. Assay Tutorial 24 Differentiating Mitochondrial Toxicity Promega touts the use of its new ToxGlo Assay to detect dysfunction early in the discovery process. Translational Medicine 52 Animal Models Get Closer to Mimicking Humans Filling the gap between translational research and the bedside is the goal of new strains that more closely reflect the human condition. NEWS Molecular Diagnostics 62 NEWS Clinical Trials OMICS Cover Nucleic Acid Sample-Prep Tools Break New Ground The solutions being developed today are as diverse as the technique and run the gamut from improving yield to enabling field use. 26 NEWS Genomics & Proteomics Tutorial 32 Quantification of Microliter Volumes of DNA According to BioDrop, its new microvolume cuvette for DNA measurement improves spectroscopy workflows. Tech Tips 34 Gene Expression Analysis Reshapes Biomedical Research Integration of technological developments with basic scientific disciplines has had profound effects. Bioprocessing Cover Up- and Downstream Go Single Use Technology has moved from simple disposable bags to complex systems that have infiltrated almost all aspects of bioprocessing. 40 CMOs Focus on Technology Improvements With capacity under control, firms are refocusing on productivity enhancements and better asset utilization. NEWS Bioprocessing Tech Note 48 Reinventing Affinity Tags BAC reports that it has done just that with its Capture Select C-Tag Affinity Resin Purification product. Tutorial 50 Mammalian Transient Transfection System Life Technologies says that Expi293 generates grams per liter levels of human IgG and non-IgG proteins. OCTOBER 1, 2012 Tutorial 56 Accelerating R&D; of Cell-Based Therapies BD has introduced cultureware surfaces that, it says, enable the expansion of cells with potential. 59 FDASIA's Impact on Novel IVDs In vitro diagnostic firms should explore how to use the new law to their advantage.

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