Genetic Engineering & Biotechnology News

JUN15 2018

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D community with critical information on the tools, technologies, and trends that drive the biotech industry.

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GENengnews.com | Genetic Engineering & Biotechnology News | JUNE 15, 2018 | 9 Phoseon, impatient with the market's seeming "paralysis by analysis," decided to launch its KeyPro decontamination system last March, well ahead of schedule. (KeyPro enables RNA researchers and lab managers to decontaminate equipment after adding re- agents and just before adding sample.) "Frankly, we typically move quicker than internal development teams," Taggard de- clares. "That means we can be more than a supplier. We can be an extension of a cus- tomer's R&D team. When a customer em- braces that model, we can help them get a product to market faster. With KeyPro, we knew we could finish the project quickly and make it available to both companies and end users, so we said, 'Let's do it!'" It's Phoseon Inside Although the KeyPro and a handful of other solutions are designed for end users, most Phoseon light sources are sold as sub- systems to OEMs throughout the world. "Development is a two-pronged approach," states Taggard. The company's engineers and scientists are focused on exploring the physi- cal, chemical, and biological interactions of light, and are wholly focused on LEDs. The goal is to continuously exceed preconceived limits of power, stability, sensitivity, and min- iaturization, and to enhance the utility of the UV LED as a light source. When Phoseon works with a client, Phos- eon staff members work closely with their client-based counterparts. "We synchronize our system with the OEM's system, run ex- periments to provide efficacy data, and have our engineers work closely with the OEM's engineers," Taggard explains. Later, Phoseon ensures that it has the information that the OEM's marketing team will need. Phoseon also gets input from end users. "There are a lot of things a UV LED can do," Taggard remarks. "It becomes a flywheel of what's possible" as customers become inter- ested in expanding applications for a solu- tion, and then continue to do more. An example of an expanding UV LED ap- plication is sterilization. In the United States, most surgical tools are disposable, but in Eu- rope, single-use instruments are discouraged. When instruments are reused, reprocessing technologies need to be thorough without im- pairing instrument function. Ultraviolet disin- fection is a reprocessing technology that deliv- ers a shorter turnaround time than chemical and heat methods can achieve. UV-C technology is another example. Be- sides being effective at disinfection, UV-C can detect and modify biological molecules. This autofluorescence capability makes it useful in highly specialized imaging. Eventually, it may be used for bedside diagnostics to identify disease states. "Our goals are pretty simple," Taggard says. "We're growing very fast, and we want that to continue." The greatest challenge in that regard, as with any disruptive technol- ogy, is overcoming market inertia. While potential customers and their end users ac- knowledge the benefits of this approach to disinfection, sterilization, decontamination, and chromatography, it takes time for OEMs to incorporate UV LED technology into their products. Eventually, that challenge will ex- pand to diagnostics. High Throughput mAb Characterization ® • Maximize epitope diversity • Identify unique epitopes • Build your IP portfolio The LSA™ instrument is a fully integrated antibody characterization instrument that uses Array SPR to analyze up to 384 bind- ing interactions simultaneously, delivering up to 100x the data in 10% of the time with 1% of the sample requirements of other systems. Combined with our application-focused analytical software, the LSA facilitates high throughput: • Kinetics screening • Epitope binning • Epitope mapping • Quantitation Contact us at: www.carterra-bio.com/lsa info@carterra-bio.com Toll free: 844-642-7635 Characterize the epitope landscape of your entire antibody library at the earliest stages of discovery to make smart decisions: On Your Radar Phoseon Technology Location 7425 NE Evergreen Parkway Hillsboro, OR 97124 Phone (503) 439-6446 Website www.phoseon.com/life-sciences Principal Bill Cortelyou President and CEO Number of Employees 150–200 Focus Phoseon Technology, a provider of UV LED technology, used to focus on industrial curing. Now the com- pany is expanding into the life sci- ences, delivering decontamination, disinfection, sterilization, and chro- matography/spectroscopy applica- tions to OEMs and end users. Vital Signs

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