Genetic Engineering & Biotechnology News

JUL 2016

Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.

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For life science research only. Not for use in diagnostic procedures. NIMBLEGEN and SEQCAP are trademarks of Roche. © 2016 Roche PP-US-05018-0716 Why waste RNA Seq reads on high expressors that have no relevance to the genes you're studying? Before sequencing, use the SeqCap RNA Enrichment System to enrich the transcripts for any number of genes that truly matter to you. • Sequence less—without sacrifi ce Maintain transcript abundance, and detect more transcripts from much less sequencing (Figure 1). • Start with ≥10 ng RNA Analyze samples with limited starting material. • Quantify and discover novel transcripts Move beyond expression profi ling to discover fusion transcripts and other isoforms that purely quantitative methods can't detect. • Analyze more samples for less Pre-capture multiplex to cost-effectively sequence more samples, and eliminate the expense of rRNA depletion. Design your own RNA target enrichment today. Visit www.nimblegen.com/SeqCapRNA for more information, or visit design.nimblegen.com to create your own human or mouse panel. SIGNIFICANTLY IMPROVE YOUR ODDS IN RNA SEQUENCING Figure 1. Preserve transcript abundance and sensitivity with 1/50th of the sequencing, as demonstrated with ERCC Controls. RNA Seq with rRNA depletion, 142.8 million reads Sample captured with SeqCap RNA Enrichment System, 2.8 million reads

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