Genetic Engineering & Biotechnology News (GEN) is the world's most widely read biotech publication. It provides the R&D; community with critical information on the tools, technologies, and trends that drive the biotech industry.
Issue link: http://gen.epubxp.com/i/155541
Contents Biobusiness CorporateProfle MiningMicrobes forPromisingTherapies 12 14 38 ProflingProblems ExploitingCells' ElectricalBehavior NEWSDiscovery&Development; NEWSBioprocessing 24 TopBiotech&Pharma; Companies Bioprocessing 18 BiomarketTrends NEWSInsideIndustry Tutorial 42 Tutorial BiopharmasDriveAntibiotic Development Bioluminescent AMPDetection NEWSProducts&Services; DEPARTMENTS Insight&Intelligence;™ 6 CRISPR/Cas ComesofAge—Almost Translational Medicine Cover TransfectionMethods 44 Manipulating Methodologiesfor ReprogrammingCells 26 The ability of clustered, regularly interspaced, short palindromic repeats to precisely and reliably cleave DNA has elevated their status. These days, small to medium-sized frms are doing all the heavy lifting in antibiotic research. 54 56 56 57 57 58 GenePatentDecision: AChemist'sView OMICS Evolving Academic research trends are driving technology advancements that are taming hard-to-transfect cell models. New Products Calendar of Events Company Index People in the News Classifed Best Science Apps Tutorial 48 BEAMingforCancer BEAMing, which combines emulsion digital PCR and fow cytometry, is being used to detect known genetic mutations in blood samples. Tutorial 36 NEWSMolecularDiagnostics NEWSGenomics&Proteomics; New and increasingly versatile strategies are laying the groundwork for novel protocols that are cost- and time-efective and also safer. DataAnalysis: Today'sNext-Gen SequencingImperative Just when you thought no more could be said about the Myriad decision, an organic chemist weighs in with an insightful analysis. Enterprising scientists are fnding ways to decipher vast NGS datasets to get the information they need to transform medicine. LegalAffairs 8 AutomatedBioreactor forAdherentCulturing Terumo BCT designed the Quantum cell-expansion system to improve the culture of adherent cells. WallStreetBiobeat 16 Researchers are harnessing the electrical capacitance of cells in media to resolve age-old bioprocess monitoring problems. Cutting-edge scientists share approaches to getting around the challenges inherent with complex biological samples. Promega reports that its new AMP-Glo Assay can be used to study biochemical regulation as well as screen for inhibitors. GEN's annual list of biotechnology and pharmaceutical frms, ranked by market cap, contains all the usual suspects and some up and comers. DrugDiscovery www.GENengnews.com Cover PurgingProtein Warp Drive Bio says it's transforming the discovery and development of natural products by using up-to-date tools like NGS. SEPTEMBER 1, 2013 • MultiparametricAssays forCardiomyocytes 50 University of Pennsylvania gene therapy team applies its expertise to HIV, pandemic infuenza, and biothreat countermeasures. According to Molecular Devices, its new platform ofers dynamic live-cell monitoring of cell beating and cytotoxicity. 52 12 AAVVectorsfor Infectious Diseases 32 NEWSClinicalTrials 52